A Few Drops at a Dose.

Incas with a Few Drops of Aryan Blood

Culture of Peripheral Blood Leucocytes for Chromosome Analysis Using a Few Drops of Whole Blood.

A number of modifications of Moorhead's original technique for culturing peripheral leucocytes have been described, enabling cultures to be grown from a few drops of blood (Arakaki and Sparkes, I963; Edwards, I962; Robinson, Bishun, Rashad, and Morton, I964). They require the use of stored calf, chick, or human serum, and this has obvious disadvantages for the small laboratory. We have, therefo...

Solving the Autism Puzzle a Few Pieces at a Time

In this issue, a pair of studies (Levy et al. and Sanders et al.) identify several de novo copy-number variants that together account for 5%-8% of cases of simplex autism spectrum disorders. These studies suggest that several hundreds of loci are likely to contribute to the complex genetic heterogeneity of this group of disorders. An accompanying study in this issue (Gilman et al.), presents ne...

Single Nucleotide Polymorphisms and Association Studies: A Few Critical Points

Uncovering DNA sequence variations that correlate with phenotypic changes, e.g., diseases, is the aim of sequence variation studies. Common types sequence variations are Single nucleotide polymorphism (SNP, pronounced snip).SNPs are the third-generation molecular marker. SNP represents a DNA sequence variant of a single base pair with the minor allele occurring in more than 1% of a given popula...

A Few Characterizations of the Univariate Continuous Distributions

Various characterizations of distributions, in their generality, are presented in terms of the conditional expectations. Some special  examples are given as well.